UNS endobody vaccines train the body to develop its own defense against agents of chronic disease.
Vaccines have been one of the most effective and impactful medicines in history. Vaccines historically target exogenous pathogens outside the body associated with infectious diseases, and there are now over a dozen infectious diseases that are preventable via vaccination, from polio to the flu.
However, traditional vaccines face challenges breaking what scientists call “immune tolerance” or the “self-barrier” when targeting endogenous proteins inside the body associated with chronic diseases. The body does not like to mount an attack against itself, even though many diseases are caused by too much of something naturally produced by the body, such as cancer cells or neurotoxic proteins as aggregated beta-amyloid peptides.
Our endobody vaccines are able to train the body to successfully break “immune tolerance” and safely and effectively produce endobodies against undesirable endogenous proteins.